When a world renowned scientist is found brutally murdered, a Harvard professor, Robert Langdon, is summoned to identify the mysterious symbol seared onto the dead man's chest. His conclusion: it is the work of the Illuminati, a secret brotherhood persumed extinet for nearly four hundred years - now reborn to continue their bitter vendetta against their sworn enemy, the Catholic church.

In Rome, the college of cardinals assembles to elect a new pope. Yet somewhere within thw walls of the Vatican, an unstoppable bomb of terryfying power relentlessly counts down to oblivion. While the minutes tick away, Langdon joins forces with Vittoria Vetra, a beautiful and mysterious Italian scientist, to decipher the labyrinthine trail of ancient symbols that snakes across Rome to the long-forgotten Illuminati lair - a secret refuge wherein lies the only hope for the vatican.

But, with each revelation comes another twist, another turn in the plot, which leaves Langdon invincible enemy...