More than two decades have passed since the events chronicled in Dune: The Butlerian Jihad. The crusade against thinking robots has ground on for years; the human worlds grow weary of war, of the bloody, inconclusive swing from victory to defeat.

The fearsome cymeks, led by Agamemnon, hatch new plots to regain their lost power from Omnius. Aurelius Venport and Norma Cenva are on the verge of the most important discovery in human history—a way to “fold” space and travel instantaneously to any place in the galaxy.

And on the faraway, nearly worthless planet of Arrakis, Selim Wormrider and his band of outlaws take the first steps towards making themselves the feared fighters who will change the course of mankind: the Fremen.